Candida Antibody Test

Candidiasis, also known as moniliasis and thrush, is caused by the organism Candida albicans. It affects the mucous membranes, skin, and nails.

Test Description

Candidiasis, also known as moniliasis and thrush, is caused by the organism Candida albicans. It affects the mucous membranes, skin, and nails. The organism is a yeast-like fungus which is normally present in vaginal secretions. Under certain circumstances, rapid growth of the organism occurs. Such circumstances include: long-term antibiotic therapy, corticosteroid therapy, pregnancy, oral contraceptives, diabetes, wearing nonventilated undergarments, and immunocompromised patients. Oral candidiasis is often noted as the first sign of AIDS. The serologic test for the Candida antibody is used in conjunction with histologic study and culture to< confirm the diagnosis and is especially useful if the other tests are inconclusive. 
 
Candida Antibody Test
 

Normal Values

Negative for Candida antibodies

Abnormal Values

  • Titer >1:8 indicates systemic infection
  • A fourfold increase in titers drawn 10 to 14 days apart indicates an acute infection.

Possible Meanings of Abnormal Values

Increased
Candida infection

Contributing Factors to Abnormal Values

  • False positive results occur in about 25% of the population.
  • Positive results can occur in patients with severe candidiasis of the skin/mucous membranes.
  • False negative results may occur in immunocompromised patients due to their inability to produce antibodies.
  • Hemolysis due to excessive agitation of the blood sample or contamination of the sample may alter test results.

Interventions/Implications

Pretest

  • Explain to the patient the purpose of the test and the need for a blood sample to be drawn.
  • The patient is to be NPO for 12 hours prior to the test

Procedure

  • A 7-mL blood sample is drawn in a red-top collection tube with no gel.
  • Gloves are worn throughout the procedure.

Posttest

  • Apply pressure at venipuncture site. Apply dressing, periodically assessing for continued bleeding.
  • Label the specimen and transport it to the laboratory.
  • Report abnormal findings to the primary care provider.

Clinical Alerts

Inform the patient of the possible need for a second blood sample, should a comparison of titers be desired.

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Dr Lobby | DrLobby.com: Candida Antibody Test
Candida Antibody Test
Candidiasis, also known as moniliasis and thrush, is caused by the organism Candida albicans. It affects the mucous membranes, skin, and nails.
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