CA-125 (Cancer Antigen 125, CA-125 Tumor Marker)

Cancer antigen-125 (CA-125) is a glycoprotein normally present in endometrial tissue and in uterine fluid.

Test Description

A tumor marker is a substance produced by body cells in response to the presence of cancer. Cancer antigen-125 (CA-125) is a glycoprotein normally present in endometrial tissue and in uterine fluid. It is not normally found in the bloodstream. It is only when there has been destruction of such tissue, as through endometrial or ovarian cancer, that CA-125 is detectible in the blood. There is a high incidence of false results with this test, making it inappropriate for use as a screening tool. The test is used to monitor response to treatment for ovarian cancer and to detect recurrence of the cancer. It is also sometimes used to monitor high-risk women who have a family history of ovarian cancer but do not yet have the disease.
CA-125

THE EVIDENCE FOR PRACTICE

There is no existing evidence that any screening test, including CA-125, ultrasound, or pelvic examination, reduces mortality from ovarian cancer. Furthermore, existing evidence that screening can detect early-stage ovarian cancer is insufficient to indicate that this earlier diagnosis will reduce mortality.

Normal Values

<35 U/mL (<35 kU/L SI units)

Possible Meanings of Abnormal Values

  • Increased
  • Acute pancreatitis
  • Breast cancer
  • Cirrhosis
  • Colon neoplasm
  • Endometrial cancer
  • Endometriosis
  • Fallopian tube cancer
  • Liver cancer
  • Lung cancer
  • Menstruation
  • Ovarian cancer
  • Pancreatic cancer
  • Pancreatitis
  • Pelvic inflammatory disease
  • Peritonitis
  • Pregnancy
  • Uterine cancer

Interventions/Implications

Pretest

  • Explain to the patient the purpose of the test and the need for a blood sample to be drawn.
  • No fasting is required before the test.

Procedure

  • A 5-mL blood sample is collected in a red-top tube.
  • Gloves are worn throughout the procedure.

Posttest

  • Apply pressure at venipuncture site. Apply dressing, periodically assessing for continued bleeding.
  • The sample is labeled and transported to the laboratory.
  • Report abnormal findings to the primary care provider.

Clinical Alerts

Patients at risk for ovarian cancer include those of low parity, decreased fertility, and delayed childbearing, with incidence increasing with age. The strongest predictor for ovarian cancer is familial evidence of ovarian cancer.

COMMENTS

BLOGGER: 2

Name

Articles for Dentists,5,Articles for Vets,18,Biochemistry Articles,11,Fish Diseases,4,Oral Health and Herbal Medicine,2,Poultry Diseases,6,Test Information,11,
ltr
item
Dr Lobby | DrLobby.com: CA-125 (Cancer Antigen 125, CA-125 Tumor Marker)
CA-125 (Cancer Antigen 125, CA-125 Tumor Marker)
Cancer antigen-125 (CA-125) is a glycoprotein normally present in endometrial tissue and in uterine fluid.
https://1.bp.blogspot.com/-Z4xHDQp_1gQ/Xt3iLLTBBxI/AAAAAAAAAI4/aDXyxTMLIVwKJNf0Ud7-K5xF3Oyo_qvQwCK4BGAsYHg/s400/CA-125.jpg
https://1.bp.blogspot.com/-Z4xHDQp_1gQ/Xt3iLLTBBxI/AAAAAAAAAI4/aDXyxTMLIVwKJNf0Ud7-K5xF3Oyo_qvQwCK4BGAsYHg/s72-c/CA-125.jpg
Dr Lobby | DrLobby.com
https://www.drlobby.com/2019/11/ca-125-cancer-antigen-125-ca-125-tumor.html
https://www.drlobby.com/
https://www.drlobby.com/
https://www.drlobby.com/2019/11/ca-125-cancer-antigen-125-ca-125-tumor.html
true
8312107627841756316
UTF-8
Loaded All Posts Not found any posts VIEW ALL Readmore Reply Cancel reply Delete By Home PAGES POSTS View All RECOMMENDED FOR YOU LABEL ARCHIVE SEARCH ALL POSTS Not found any post match with your request Back Home Sunday Monday Tuesday Wednesday Thursday Friday Saturday Sun Mon Tue Wed Thu Fri Sat January February March April May June July August September October November December Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec just now 1 minute ago $$1$$ minutes ago 1 hour ago $$1$$ hours ago Yesterday $$1$$ days ago $$1$$ weeks ago more than 5 weeks ago Followers Follow THIS PREMIUM CONTENT IS LOCKED STEP 1: Share to a social network STEP 2: Click the link on your social network Copy All Code Select All Code All codes were copied to your clipboard Can not copy the codes / texts, please press [CTRL]+[C] (or CMD+C with Mac) to copy Table of Content